Aim and objective: The aim of the article was to evaluate and compare the antimicrobial effect of alcoholic and hydroalcoholic extracts of Decalepis hamiltonii with those of Curcuma longa, Azadirachta indica, and Zingiber officinale against Enterococcus faecalis.
Materials and methods: Alcoholic and hydroalcoholic extracts of the herbs were prepared by cold maceration and filtration–decantation process. Minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) were determined for each extract; zone of inhibition (ZOI) was assessed separately for each extract and their different combinations on both laboratory strain and clinical isolates of E. faecalis.
Results: The extracts of D. hamiltonii showed a significant antimicrobial action, against endodontic pathogen E. faecalis, both independently and in combination preparations.
Conclusion: Extract of D. hamiltonii can be used as intracanal irrigant and medicament in endodontics after confirming its biocompatibility.
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