Aim: To evaluate and compare the resistance to fracture of simulated human immature teeth treated with MTA/Biodentine as apical barrier, reinforced with a novel anatomic post. Materials and methods: Eighty extracted maxillary central incisors were used in this study. Access opening was done, and ProTaper rotary instruments up to F3 were used to prepare the root canal. Peeso reamers were used sequentially up to size 6 (1.7 mm) with 1 mm beyond the apex to simulate immature teeth. Irrigation with 2.5% sodium hypochlorite (NaOCl) and 17% ethylenediaminetetraacetic acid (EDTA) was done. They were then divided into two groups (n = 40 each) according to the apical barrier used for apexification: group I—apical barrier using Biodentine and group II—apical barrier using MTA. Each group was then divided into four subgroups: subgroup A (n = 10)—apical barrier using Biodentine/MTA with no obturation, subgroup B (n = 10)—apical barrier using Biodentine/MTA with everStick post as reinforcement, subgroup C (n = 10)—apical barrier using Biodentine/MTA with complete filling using the same material used for apical barrier, and subgroup D (n = 10)—apical barrier using Biodentine/MTA with prefabricated glass fiber post as reinforcement. All samples were incubated for two weeks at 37°C before subjecting to fracture testing using the Universal Testing Machine. A compressive load was applied at 135° to the long axis of the tooth. Results: Statistical analysis was done using one-way ANOVA test and post hoc Bonferroni test. In the above tests, p value less than 0.05 (p < 0.05) was taken to be statistically significant. Conclusion: A novel anatomic post, everStick post is a viable option for reinforcement of teeth with immature root apex and thin dentinal walls after apexification.