Journal of Operative Dentistry & Endodontics

Register      Login

VOLUME 1 , ISSUE 2 ( July-December, 2016 ) > List of Articles

RESEARCH ARTICLE

Comparative Evaluation of Antibacterial Efficacy of Four Toothpastes and Mouthwashes against Streptococcus mutans and Lactobacillus: An in vivo Study

Jonathan E Sam, Paulaian Benin, Ruth H Beaulah, Gnanaseelan, Lal Krishna, Jacob Raja

Citation Information : Sam JE, Benin P, Beaulah RH, G, Krishna L, Raja J. Comparative Evaluation of Antibacterial Efficacy of Four Toothpastes and Mouthwashes against Streptococcus mutans and Lactobacillus: An in vivo Study. J Oper Dent Endod 2016; 1 (2):60-65.

DOI: 10.5005/jp-journals-10047-0013

Published Online: 01-12-2016

Copyright Statement:  Copyright © 2016; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background

Cariogenic microorganisms are the most important cause for occurrence of dental caries. Dentifrices and mouthwashes containing antimicrobial substances are proven to be effective in the eradication of these pathogens from the oral cavity.

Aim

To evaluate the antimicrobial efficacy of fluoride, chlorhexidine (CHX), herbal, and xylitol containing toothpastes and mouthwashes against Streptococcus mutans (S. mutans) and Lactobacillus (LB) in subjects within the age group of 18 to 22 years at time intervals of 1, 3, and 6 months.

Materials and methods

One hundred subjects were randomly divided into four groups. Group I: fluoride, group II: chlorhexidine, group III: herbal, group IV: xylitol and instructed to use toothpastes and mouthwashes containing the specific agents. Salivary samples were collected to evaluate the levels of S. mutans and LB at baseline, 1, 3, and 6 months. Bacterial levels were evaluated using caries risk test (CRT) kit. Data were analyzed using analysis of variance and post hoc test.

Results

During intragroup comparison, S. mutans levels in group I showed statistically significant difference among the four time intervals. On intergroup comparison, S. mutans levels after 6 months for groups I, II, III, and IV were 1.12, 1.16, 1.28, and 1.4 respectively.

Conclusion

It can be concluded that fluoride, CHX, and xylitol showed a significant reduction in S. mutans and LB count after a time period of 6 months while herbal group did not show a significant reduction in S. mutans and LB count at any intervals.

How to cite this article

Sam JE, Benin P, Beaulah RH, Gnanaseelan, Krishna L, Raja J. Comparative Evaluation of Antibacterial Efficacy of Four Toothpastes and Mouthwashes against Streptococcus mutans and Lactobacillus: An in vivo Study. J Oper Dent Endod 2016;1(2):60-65.


PDF Share
  1. Treatment protocols: Non fluoride management of the caries disease process and available diagnostics. Dent Clin North Am 2010 Jul;54(3):527-540.
  2. Role of Streptococcus mutans in dental decay. Microbiol Rev 1986 Dec;50(4):353-379.
  3. The role of bacteria in the caries process: Ecological perspectives. J Dent Res 2011 Mar;90(3):294-303.
  4. The science and practice of caries prevention. J Am Dent Assoc 2000 Jul;131(7):887-899.
  5. Are dental diseases examples of ecological catastrophes? Microbiol 2003 Feb;149(2):279-294.
  6. The role of chlorhexidine in caries prevention. Oper Dent 2008 Nov-Dec;33(6):710-716.
  7. Ethnomedicine: Use in dental caries. Braz J Oral Sci 2007 Apr-Jun;6(21):1308-1312.
  8. Maintaining mutans streptococci suppression: with xylitol chewing gum. J Am Dent Assoc 2000 Jul;131(7):909-916.
  9. Caries risk assessment in practice for age 6 through adults. J Calif Dent Assoc 2007 Oct;35(10):703-707.
  10. Chairside testing for cariogenic bacteria: current concepts and clinical strategies. J Min Interven Dent 2008 Jul;1(2):126-147.
  11. High-fluoride toothpaste: a multicenter randomized controlled trial in adults. Community Dent Oral Epidemiol 2014 Aug;42(4):333-340.
  12. Efficacy of xylitol and fluoride mouthrinses on salivary mutans streptococci. Asian Pac J Trop Biomed 2011 Dec;1(6):488-490.
  13. The caries balance: the basis for caries management by risk assessment. Oral Health Prev Dent 2004;2(1): 259-264.
  14. Development of oral bacterial flora in young children. Ann Med 2000 Mar;32(2):107-112.
  15. Benefits of topical fluorides firmly established. Evid Based Dent 2004;5(2):36-37.
  16. Mutans streptococci suppression by chlorhexidine gel in toddlers. Am J Dent 1999 Apr;12(2):89-91.
  17. Mutans streptococci dose response to xylitol chewing gum. J Dent Res 2006 Feb;85(2):177-181.
  18. In vitro antimicrobial effect of crude miswak extract on oral pathogen. Saudi Dent J 2002 Jan-Apr;14(1):26-32.
  19. Influence of a fluoride mouthrinse on mutans streptococci in school children. Caries Res 2006;40(6):501-507.
  20. Six months of daily high-dose xylitol in high-risk school children: a randomized clinical trial on plaque pH and salivary mutans streptococci. Caries Res 2009 Dec;43(6):455-461.
  21. Potential efficiency of chlorhexidine against mutans streptococci and human dental caries. J Dent Res 1994 Mar;73(3):628-629.
  22. A review on phytochemical and pharmacological investigations of miswak. J Pharm Bioallied Sci 2011 Jan-Mar;3(1):113-117.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.